Amber Heard has filed for divorce from Johnny Depp, citing irreconcilable differences.
The two have been married for about 15 months.
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Heard, 30, filed the papers in Los Angeles earlier this week. She is seeking spousal support from Depp, 52; the pair have no children together.
The marriage was Depp’s second and Heard’s first.
Their separation date was listed as Sunday, May 22, according to an Associated Press report.
Depp has a new film coming out Friday, Alice Through the Looking Glass. Heard appears to have been absent for both Monday’s premiere in L.A. as well as the London premiere of the film on May 10.
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Recently the pair was embroiled in legal trouble with Australian officials after Heard smuggled their two pet dogs into the country. Heard pleaded guilty to falsifying documents to conceal the pets while arriving via private jet.
They appeared in a bizarre PSA video for the government of Australia to avoid a conviction for Heard.
Following the legal battle, Depp became embroiled in a war of words with Australia’s Deputy Prime Minister, Barnaby Joyce, which included Depp suggesting the lawmaker was inbred with a vegetable.
WATCH: Johnny Depp says Australian Deputy PM was “inbred with a tomato”
On Wednesday, Joyce told reporters that Depp’s comments proved he had gotten into Johnny Depp’s head like fictional serial killer Hannibal Lecter.
WATCH: Australia’s Deputy PM says he is Johnny Depp’s Hannibal Lecter
Joyce followed up those comments a day later saying he would not joke about the couple’s “relationship breakdown.”
WATCH: Australia’s Deputy PM refuses to ‘revel’ in Depp, Heard’s divorce
Depp and Heard met while filming The Rum Diary in 2011.